The effect of lycopene on cell growth and oxidative DNA damage of Hep3B human hepatoma cells.

@article{Park2005TheEO,
  title={The effect of lycopene on cell growth and oxidative DNA damage of Hep3B human hepatoma cells.},
  author={Yun Ok Park and E S Hwang and Tae Wha Moon},
  journal={BioFactors},
  year={2005},
  volume={23 3},
  pages={129-39}
}
Lycopene, the predominant carotenoid in tomatoes and tomato-based foods, is reported to protect against various cancers, especially prostate cancer. We investigated the effect of lycopene on DNA damage and cell growth inhibition in the Hep3B human hepatoma cell line. Lycopene was analyzed by HPLC, and cell proliferation was determined by 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) assay. A final lycopene concentration of 0.1-50 microM was added to cells plated in 96-well… CONTINUE READING
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