The effect of luteinizing hormone-releasing factor and its agonist on cultured human granulosa cells.

@article{Casper1982TheEO,
  title={The effect of luteinizing hormone-releasing factor and its agonist on cultured human granulosa cells.},
  author={Robert F. Casper and Gregory F. Erickson and Robert W. Rebar and Samuel Yen},
  journal={Fertility and sterility},
  year={1982},
  volume={37 3},
  pages={406-9}
}
The possible direct effect of luteinizing hormone-releasing factor (LRF) and a potent LRF agonist, [D-Trp6,Pro9NEt]-LRF (LRF-Ag), on basal and follicle-stimulating hormone (FSH)-stimulated estrogen and progesterone production by cultured human granulosa cells was examined. Granulosa cells, collected from healthy follicles (4 to 12 mm in diameter) in the early to midfollicular phase were grown for 2 days in serum-free medium with aromatase substrate (androstenedione; 10(-7) M) and human FSH (100… CONTINUE READING