The effect of lithium administration in animal models of depression: a short review.

@article{Redrobe1999TheEO,
  title={The effect of lithium administration in animal models of depression: a short review.},
  author={John Paul Redrobe and Michel S Bourin},
  journal={Fundamental & clinical pharmacology},
  year={1999},
  volume={13 3},
  pages={293-9}
}
The aim of this short review was to collate the data involving the effects of lithium alone, or in combination, with antidepressant drugs in several animal models of depression. It has been shown that lithium administration reduced immobility in the mouse forced swimming test when given 30 min, but not 45 min, before testing. Further studies indicated that… CONTINUE READING