The effect of linkage disequilibrium and deviation from Hardy–Weinberg proportions on the changes in genetic variance with bottlenecking

@article{Wang1998TheEO,
  title={The effect of linkage disequilibrium and deviation from Hardy–Weinberg proportions on the changes in genetic variance with bottlenecking},
  author={Jinliang Wang and Armando Caballero and W G Hill},
  journal={Heredity},
  year={1998},
  volume={81},
  pages={174-186}
}
A growing body of experimental work has shown that the additive genetic variance of fitness components can increase following a founder event or a bottleneck of population size. This is usually explained theoretically by the conversion of dominance variance and/or epistatic variance to additive variance following bottlenecks. The present analysis considers the effects of deviation from Hardy–Weinberg proportions (DHW) and linkage disequilibrium (LD) caused by bottlenecks. It is shown that DHW… CONTINUE READING
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