The effect of lead intoxication on endocrine functions.

  title={The effect of lead intoxication on endocrine functions.},
  author={Konstantinos K. Doumouchtsis and Stergios K. Doumouchtsis and Evangelos K Doumouchtsis and Despina N. Perrea},
  journal={Journal of endocrinological investigation},
  volume={32 2},
Studies on the effects of lead on the endocrine system are mainly based on occupationally lead-exposed workers and experimental animal models. Although evidence is conflicting, it has been reported that accumulation of lead affects the majority of the endocrine glands. In particular, it appears to have an effect on the hypothalamic-pituitary axis causing blunted TSH, GH, and FSH/LH responses to TRH, GHRH, and GnRH stimulation, respectively. Suppressed GH release has been reported, probably… CONTINUE READING
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