The effect of lanthanum carbonate on calciprotein particles in hemodialysis patients

  title={The effect of lanthanum carbonate on calciprotein particles in hemodialysis patients},
  author={Kimihiko Nakamura and Yudai Nagata and Toshiya Hiroyoshi and Naohito Isoyama and Koki Fujikawa and Yutaka Miura and Hideyasu Matsuyama and Makoto Kuro-o},
  journal={Clinical and Experimental Nephrology},
  pages={323 - 329}
Background Aggregation of solid-phase calcium–phosphate and fetuin-A form nanoparticles called calciprotein particles (CPP). Serum CPP levels are increased in CKD patients and correlated with vascular stiffness and calcification. In this study, we evaluated effects of lanthanum carbonate (LC) and calcium carbonate (CC) on serum CPP levels in hemodialysis (HD) patients. Methods Twenty-four (24) HD patients (50% men, age; 68 ± 12 years, dialysis period; 6.2 ± 4.8 years, K t/v; 1.74 ± 0.34) were… Expand
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A phosphate-centric paradigm for pathophysiology and therapy of chronic kidney disease
  • M. Kuro-o
  • Medicine
  • Kidney international supplements
  • 2013
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