The effect of labeling parameters on perfusion-based fMRI in nonhuman primates.

@article{Zappe2008TheEO,
  title={The effect of labeling parameters on perfusion-based fMRI in nonhuman primates.},
  author={Anne Catherin Zappe and Josef Pfeuffer and Hellmut Merkle and Nikos K. Logothetis and Jozien B. M. Goense},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2008},
  volume={28 3},
  pages={640-52}
}
The blood oxygenation level-dependent (BOLD) signal is the most commonly used modality of functional magnetic resonance imaging (fMRI) today. Although easy to implement, it is an ambiguous signal since it results from a combination of several hemodynamic factors. Functional cerebral blood flow changes, as measured by using arterial spin labeling (ASL), typically occur in the parenchyma and have been demonstrated to be more closely coupled to neural activation compared with BOLD. However, the… CONTINUE READING
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Magnetic resonance imaging: physical principles and sequence design

  • EM Haacke, JW Brown, L Thompson, R Venkatesan
  • 1999
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