The effect of ketamine on the MACBAR of sevoflurane in dogs.

  title={The effect of ketamine on the MACBAR of sevoflurane in dogs.},
  author={Lydia C Love and Christine M. Egger and Barton W. Rohrbach and Sherry Cox and Meredith Hobbs and Thomas J Doherty},
  journal={Veterinary anaesthesia and analgesia},
  volume={38 4},
OBJECTIVE To determine the effect of intravenous ketamine on the minimum alveolar concentration of sevoflurane needed to block autonomic response (MAC(BAR)) to a noxious stimulus in dogs. STUDY DESIGN Randomized, crossover, prospective design. ANIMALS Eight, healthy, adult male, mixed-breed dogs, weighing 11.2-16.1 kg. METHODS Dogs were anesthetized with sevoflurane on two occasions, 1 week apart, and baseline MAC(BAR) (B-MAC(BAR)) was determined on each occasion. MAC(BAR) was defined as… CONTINUE READING

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