The effect of irradiation modification and RGD sequence adsorption on the response of human osteoblasts to polycaprolactone.

@article{Marletta2005TheEO,
  title={The effect of irradiation modification and RGD sequence adsorption on the response of human osteoblasts to polycaprolactone.},
  author={Giovanni Marletta and Gabriela Ciapetti and Cristina Satriano and Stefania Pagani and Nicola Baldini},
  journal={Biomaterials},
  year={2005},
  volume={26 23},
  pages={
          4793-804
        }
}
Using techniques of tissue engineering, synthetic substitutes can be applied for the repair and regeneration of damaged bone. It has been found that material surface properties are crucial for cell adhesion and spreading, i.e. cell activities that are related directly to the ability of osteoblasts to proliferate. This fact has promoted the strategy of creating an ECM-like layer onto materials, so as to influence the cell response. In this study human bone-derived osteoblasts have been used to… CONTINUE READING

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