The effect of interferon-beta on blood-brain barrier disruptions demonstrated by contrast-enhanced magnetic resonance imaging in relapsing-remitting multiple sclerosis.

@article{Stone1995TheEO,
  title={The effect of interferon-beta on blood-brain barrier disruptions demonstrated by contrast-enhanced magnetic resonance imaging in relapsing-remitting multiple sclerosis.},
  author={Lael Stone and Joseph A. Frank and Paul S. Albert and C N Bash and Marshall E. Smith and Heidi Wynn Maloni and Henry F. McFarland},
  journal={Annals of neurology},
  year={1995},
  volume={37 5},
  pages={611-9}
}
Magnetic resonance imaging (MRI) has been a valuable tool to understand the pathophysiology and natural history of multiple sclerosis (MS), and increasing attention is focusing on the use of MRI findings as outcome measures in treatment trials in MS. The recently completed trial of interferon-beta-1b (IFN-beta 1b) demonstrated a decrease in accumulation of… CONTINUE READING