The effect of inorganic salts on the ketone decomposition of oxaloacetic acid.

@article{Krebs1942TheEO,
  title={The effect of inorganic salts on the ketone decomposition of oxaloacetic acid.},
  author={Hans Adolf Sir Krebs},
  journal={The Biochemical journal},
  year={1942},
  volume={36 3-4},
  pages={
          303-5
        }
}
Oxaloacetic acid is known to decompose in aqueous solution into pyruvic acid and CO2. AtpH 4 and 200 the rate of the 'ketone decomposition' varies between 6 and 18% per hr. The fact that this 'spontaneous' decomposition shows considerable variations suggests that trace impurities might affect the stability of oxaloacetic acid. Krampitz & Werkman [1941] recently reported that Mg ions accelerate the decomposition; this makes it probable that the impurities in question are inorganic salts. The… CONTINUE READING

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