The effect of injected RGD modified alginate on angiogenesis and left ventricular function in a chronic rat infarct model.

@article{Yu2009TheEO,
  title={The effect of injected RGD modified alginate on angiogenesis and left ventricular function in a chronic rat infarct model.},
  author={Jiashing Yu and Yiping Gu and Kim T Du and Shirley S. Mihardja and Richard E. Sievers and Randall J. Lee},
  journal={Biomaterials},
  year={2009},
  volume={30 5},
  pages={751-6}
}
Congestive heart failure (CHF) is a chronic disease with a high mortality rate. Managing CHF patients has been one of the most severe health care problems for years. Scaffold materials have been predominantly investigated in acute myocardial infarction (MI) studies and have shown promising improvement in LV function. In this study we examined whether surface modification of a biomaterial can influence the myocardial microenvironment and improve myocardial function in a rodent model of ischemic… CONTINUE READING

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Microvascular transport model predicts oxygenation changes in the infarcted heart after treatment.

American journal of physiology. Heart and circulatory physiology • 2007
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