The effect of infusion of mannitol-sodium bicarbonate on the clinical course of myoglobinuria.

@article{Eneas1979TheEO,
  title={The effect of infusion of mannitol-sodium bicarbonate on the clinical course of myoglobinuria.},
  author={J F Eneas and Paul Schoenfeld and Michael H. Humphreys},
  journal={Archives of internal medicine},
  year={1979},
  volume={139 7},
  pages={801-5}
}
Twenty patients who had evidence of myoglobinuria were treated with intravenous infusions of mannitol and sodium bicarbonate. Nine patients (group 1) responded with higher urine output, and continued infusion improved renal function; none required dialysis and all survived. Eleven patients (group 2) did not respond to the infusion, and required an average of 5.3 (range, 0 to 11) dialyses; one patient died. There was no significant difference in initial BUN level, creatinine level, BUN… CONTINUE READING
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