The effect of indomethacin on acute radiation induced gastrointestinal injury: a morphologic study.

Abstract

Radiation-induced intestinal injury is a dose limiting factor in the treatment of pelvic, abdominal, and retroperitoneal malignancies with radiation therapy. In experimental models, radiation has been associated with increased intestinal prostaglandin activity and in clinical trials prostaglandin inhibitors have been demonstrated to improve the symptoms of… (More)

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@article{Rose1992TheEO, title={The effect of indomethacin on acute radiation induced gastrointestinal injury: a morphologic study.}, author={P. G. Rose and Susan A. Halter and C. M. Su}, journal={Journal of surgical oncology}, year={1992}, volume={49 4}, pages={231-8} }