The effect of increased CSF pressure on interstitial fluid flow during ventriculocisternal perfusion in the cat.


Transependymal absorption of cerebrospinal fluid (CSF) in hydrocephalus is suggested by periventricular edema, but the necessary bulk flow of interstitial fluid (ISF) has not been found. We performed ventriculocisternal perfusions in adult cats using CSF with the extracellular marker [3H]sucrose. CSF pressure was maintained at -5(control), 20 or 40 cm H2O… (More)


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