The effect of incorporation of indomethacin with polyethylene glycol 6000 in a solid dispersion on itsin vivo properties in the rat

Abstract

Preparations of indomethacin and indomethacin in combination with PEG 6000 were administered in solid form by the oral route to male rats. No significant differences in anti-oedema activity were observed between the different preparations of indomethacin, but high blood levels of drug were observed following dosing with indomethacin, in a PEG 6000 melt… (More)
DOI: 10.1007/BF01972373

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