The effect of implanting gentamicin-impregnated polymethylmethacrylate beads in the tarsocrural joint of the horse.

Abstract

OBJECTIVE To determine the effect of intra-articular gentamicin-impregnated polymethylmethacrylate (PMMA) beads inserted in the equine tarsocrural joint on the synovial fluid, synovial lining, and cartilage, and to determine the peak and sustainable gentamicin concentrations in synovial fluid and plasma. STUDY DESIGN Pharmacokinetic, cytologic, and… (More)

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