The effect of immune globulin on the response to trivalent oral poliovirus and yellow fever vaccinations.

@article{Kaplan1984TheEO,
  title={The effect of immune globulin on the response to trivalent oral poliovirus and yellow fever vaccinations.},
  author={JonathanE. Kaplan and Donald B. Nelson and LawrenceB. Schonberger and Milford H. Hatch and Thomas P Monath and JohnS. Lazuick and Charles H Calisher and FranzW. Rosa},
  journal={Bulletin of the World Health Organization},
  year={1984},
  volume={62 4},
  pages={
          585-90
        }
}
To assess whether immune globulin may be administered concurrently with trivalent oral poliovirus vaccine (OPV) or yellow fever vaccine, antibody responses were studied in Peace Corps volunteers embarking for overseas duty in 1978. Of 200 volunteers who received OPV, 192 (96%) had pre-existing neutralizing antibody to at least 2 poliovirus types; of 160 yellow fever vaccinees, 24 (15%) had pre-existing 17D yellow fever antibody. Each volunteer received 5 ml of immune globulin, 0-7 days before… CONTINUE READING

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