The effect of hypertension on the response to blood loss in a rodent model.

@article{Sinert2000TheEO,
  title={The effect of hypertension on the response to blood loss in a rodent model.},
  author={Richard H. Sinert and Patr{\'i}cia Guerrero and Elaine Quintana and Shahriar Zehtabchi and Chang Nam Kim and A Agbemadzo and Bonny J. Baron},
  journal={Academic emergency medicine : official journal of the Society for Academic Emergency Medicine},
  year={2000},
  volume={7 4},
  pages={318-26}
}
OBJECTIVE Hypertensive patients having higher baseline peripheral resistance and sympathetic tone than normotensive patients may have aberrant responses to hemorrhage. In an attempt to further characterize this clinical observation, the authors compared the hemodynamic and metabolic responses to hemorrhage between spontaneously hypertensive rats (SHR) and normotensive rats (NTR). METHODS Twenty adult rats (10 NTR and 10 SHR) were anesthetized with althesin via the intraperitoneal route… CONTINUE READING
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