The effect of hydroxyurea and mitomycin C on sperm motility in mice.

@article{Ficsor1980TheEO,
  title={The effect of hydroxyurea and mitomycin C on sperm motility in mice.},
  author={G. Ficsor and Leonard C. Ginsberg},
  journal={Mutation research},
  year={1980},
  volume={70 3},
  pages={383-7}
}
The mutagen, mitomycin C, and the teratogen, hydroxyurea, were found to decrease sperm motility in mice in a dose-dependent manner. Positive results with these compounds suggest that sperm motility may have been decreased through either mutations or developmental disturbances. Sperm motility can be determined quickly and may be done in conjunction with a sperm-morphology assay.