The effect of high-dose medium- and long- term progestogen exposure on endometrial vessels.

@article{Song1995TheEO,
  title={The effect of high-dose medium- and long- term progestogen exposure on endometrial vessels.},
  author={Jonathan Y. Song and Robert Markham and P. D. Hyde G. Russell and Terence A. Wong and Leonie Young and Ian Stewart Fraser},
  journal={Human reproduction},
  year={1995},
  volume={10 4},
  pages={797-800}
}
A total of 19 paraffin-embedded endometrial tissue blocks were obtained from high-dose progestogen-exposed patients. A labelled streptavidin-biotin-alkaline phosphatase method was used with antibodies against von Willebrand factor (vWF) and CD34. The density of CD34 and vWF positive (CD34+ and vWF+) vessels in progestogen-exposed endometria (103 +/- 9.6/mm2 and 106 +/- 8.7/mm2) was significantly lower than in endometria from women with normal cycles (169 +/- 9.3/mm2 and 136 +/- 8.0/mm2) (P < 0… CONTINUE READING

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