The effect of high concentration of magnesium with ropivacaine, gentamicin, rocuronium, and their combination on neuromuscular blockade

@article{Rhee2015TheEO,
  title={The effect of high concentration of magnesium with ropivacaine, gentamicin, rocuronium, and their combination on neuromuscular blockade},
  author={Won Ji Rhee and Seung Yoon Lee and J. H. Lee and S. Choi and Seung-Cheol Lee and Jong Hwan Lee and Soo-il Lee},
  journal={Korean Journal of Anesthesiology},
  year={2015},
  volume={68},
  pages={50 - 61}
}
Background Magnesium, ropivacaine, gentamicin, and rocuronium block neuromuscular (NM) transmission by different mechanisms. Therefore, concurrent administration of these agents may induce prolonged muscle paralysis via synergistic interaction. This study investigated the efficacy and safety of NM block caused by the administration of high concentrations of magnesium in combination with ropivacaine, gentamicin, and rocuronium. Methods Eighty-three left phrenic nerve-hemidiaphragms from male SD… Expand
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