The effect of haemodilution with 6% hydroxyethyl starch (130/0.4) on haemostasis in pregnancy: an in-vitro assessment using thromboelastometry.

@article{Ansari2010TheEO,
  title={The effect of haemodilution with 6% hydroxyethyl starch (130/0.4) on haemostasis in pregnancy: an in-vitro assessment using thromboelastometry.},
  author={Tarek Ansari and Waleed Riad},
  journal={European journal of anaesthesiology},
  year={2010},
  volume={27 3},
  pages={304-5}
}
Editor, Hydroxyethyl starch (HES) preparations are more effective than lactated Ringer’s solution in maintaining blood volume after rapid blood loss, but their use is limited by concerns over their effect on haemostasis. HES causes a reduction in circulating factor VIII and von Willebrand factor (VWF) that is not explained by the effect of dilution alone, and it also inhibits platelet function and fibrin polymerization. Low or medium molecular weight HES with low substitution seems to have a… CONTINUE READING

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