The effect of growth rate in continuous-flow cultures on the replication of rubella virus in BHK cells.

@article{Kilburn1970TheEO,
  title={The effect of growth rate in continuous-flow cultures on the replication of rubella virus in BHK cells.},
  author={Douglas G. Kilburn and A L van Wezel},
  journal={The Journal of general virology},
  year={1970},
  volume={9 1},
  pages={
          1-7
        }
}
Summary Baby hamster kidney cells infected with rubella virus were grown in continuous flow culture to investigate the effect of growth rate on virus replication. Both cell and virus concentration varied with growth rate in normal Eagle's medium but were independent of growth rate in phosphate-limited medium. In both media, virus production rate increased with increasing growth rate but there was a concomitant increase in the fraction of the cell population that was shedding virus, so it is not… CONTINUE READING

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