The effect of growth hormone replacement on the thyroid axis in patients with hypopituitarism: in vivo and ex vivo studies.

@article{Glynn2017TheEO,
  title={The effect of growth hormone replacement on the thyroid axis in patients with hypopituitarism: in vivo and ex vivo studies.},
  author={Nigel Glynn and Helena C. Kenny and Leah R Quisenberry and David John Halsall and Paul R Cook and Tommy Kyaw Tun and John H McDermott and Diarmuid Smith and Christopher J Thompson and Donal O'Gorman and Anita Boelen and Joaqu{\'i}n Lado-Abeal and Amar Agha},
  journal={Clinical endocrinology},
  year={2017},
  volume={86 5},
  pages={747-754}
}
OBJECTIVE Alterations in the hypothalamic-pituitary-thyroid axis have been reported following growth hormone (GH) replacement. The aim was to examine the relationship between changes in serum concentration of thyroid hormones and deiodinase activity in subcutaneous adipose tissue, before and after GH replacement. DESIGN A prospective, observational study of patients receiving GH replacement as part of routine clinical care. PATIENTS Twenty adult hypopituitary men. MEASUREMENTS Serum TSH… CONTINUE READING

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