The effect of food on plasma and tissue concentrations of linezolid after multiple doses.

Abstract

In the present pilot study we investigated the effect of food ingestion on target site pharmacokinetics of linezolid, the first clinically approved oxazolidinone. For this purpose we determined free concentrations of linezolid at steady state in the interstitial space fluid of skeletal muscle and subcutaneous adipose tissue under fasting and non-fasting… (More)

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@article{Islinger2006TheEO, title={The effect of food on plasma and tissue concentrations of linezolid after multiple doses.}, author={Florian Islinger and Pejman Dehghanyar and Robert Sauermann and Cornelia Buerger and Charlotte Kloft and Markus M{\"{u}ller and Christian Joukhadar}, journal={International journal of antimicrobial agents}, year={2006}, volume={27 2}, pages={108-12} }