The effect of flaxseed supplementation on body weight and body composition: a systematic review and meta‐analysis of 45 randomized placebo‐controlled trials

@article{MohammadiSartang2017TheEO,
  title={The effect of flaxseed supplementation on body weight and body composition: a systematic review and meta‐analysis of 45 randomized placebo‐controlled trials},
  author={M. Mohammadi-Sartang and Z. Mazloom and H. Raeisi-Dehkordi and R. Barati-Boldaji and N. Bellissimo and J. O. Totosy de Zepetnek},
  journal={Obesity Reviews},
  year={2017},
  volume={18},
  pages={1096 - 1107}
}
Flaxseed consumption may be inversely associated with obesity; however, findings of available randomized controlled trials (RCTs) are conflicting. The present study aimed to systematically review and analyse RCTs assessing the effects of flaxseed consumption on body weight and body composition. PubMed, Medline via Ovid, SCOPUS, EMBASE and ISI Web of Sciences databases were searched up to November 2016. Mean changes in body composition indices including body weight, body mass index (BMI) and… Expand
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This meta-analysis of RCTs showed significant reductions in both systolic BP and diastolic BP following supplementation with various flaxseed products. Expand
Meta-analysis of the effects of flaxseed interventions on blood lipids.
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Flaxseed significantly reduced circulating total and LDL-cholesterol concentrations, but the changes were dependent on the type of intervention, sex, and initial lipid profiles of the subjects. Expand
Flaxseed Supplementation in Metabolic Syndrome Management: A Pilot Randomized, Open‐labeled, Controlled Study
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It is indicated that co‐administration of flaxseed with lifestyle modification is more effective than lifestyle modification alone in management of MetS; whether these effects will be sustained with longer treatment durations remains to be determined. Expand
The effects of flaxseed dietary supplement on lipid profile, bone mineral density, and symptoms in menopausal women: a randomized, double-blind, wheat germ placebo-controlled clinical trial.
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It is suggested that 1-yr incorporation of flaxseed into the diet produced a favorable, but not clinically significant, effect on blood cholesterol and caused no significant change in BMD or symptoms in healthy menopausal women. Expand
Low dose Flaxseed Oil Supplementation Alters the Fatty Acids Profile and the Progression of Metabolic Syndrome in Men without Adequate Medical Treatment
TLDR
In conclusion, low daily doses of flaxseed oil may improve clinical and metabolic parameters in middle-aged men without adequate treatment for metabolic syndrome. Expand
A randomized trial of the effects of flaxseed to manage constipation, weight, glycemia, and lipids in constipated patients with type 2 diabetes
TLDR
In constipated patients with T2D, flaxseed cookies used as a snack may be a useful tool for decreasing constipation symptoms, weight, glycemic and lipid levels. Expand
Impact of weight loss diet associated with flaxseed on inflammatory markers in men with cardiovascular risk factors: a clinical study
TLDR
This study suggests that flaxseed added to a weight loss diet could be an important nutritional strategy to reduce inflammation markers such as CRP and TNF-α. Expand
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In conclusion, flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management. Expand
Effects of a Flaxseed-Derived Lignan Supplement in Type 2 Diabetic Patients: A Randomized, Double-Blind, Cross-Over Trial
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Daily lignan supplementation resulted in modest, yet statistically significant improvements in glycemic control in type 2 diabetic patients without apparently affecting fasting glucose, lipid profiles and insulin sensitivity. Expand
Additive effect of linseed oil supplementation on the lipid profiles of older adults
TLDR
The results suggest that the nutritional intervention was effective, but linseed oil showed notable effects by increasing the HDL cholesterol concentration, demonstrating the importance of reducing the consumption of saturated fat. Expand
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