The effect of extracellular matrix proteins on the cellular response of HUVECS and HOBS after covalent immobilization onto titanium.

@article{Heller2015TheEO,
  title={The effect of extracellular matrix proteins on the cellular response of HUVECS and HOBS after covalent immobilization onto titanium.},
  author={Martin Heller and Peer Wolfgang K{\"a}mmerer and Bilal Al-Nawas and Marie-Anne Luszpinski and Renate F{\"o}rch and Juergen Brieger},
  journal={Journal of biomedical materials research. Part A},
  year={2015},
  volume={103 6},
  pages={2035-44}
}
Biomimetic surface modifications are regarded as promising approach to stimulate cellular behavior at the interface of implant materials. Aim of the study was an evaluation of the cellular response of human umbilical cord cells (HUVECS) and human osteoblasts (HOBS) on titanium covalently coated with the extracellular matrix (ECM) proteins fibrinogen, collagen, laminin, and osteopontin. For the surface modification, titanium discs were first amino-functionalized by plasma polymerization of… CONTINUE READING
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