The effect of exercise on natural killer cell activity in young and old subjects.

@article{Fiatarone1989TheEO,
  title={The effect of exercise on natural killer cell activity in young and old subjects.},
  author={M A Fiatarone and J Eileen Morley and Eda T. Bloom and David Benton and George F. Solomon and Takashi Makinodan},
  journal={Journal of gerontology},
  year={1989},
  volume={44 2},
  pages={M37-45}
}
Alterations in immune function have been commonly reported in elderly persons. We have examined the effect of age on the responsiveness of natural killer (NK) cells to in vitro stimulation with recombinant interleukin-2 (rIL-2) and in vivo stimulation with exercise in 17 healthy subjects (8 young and 9 old). The old subjects were found to have NK cell numbers and function that were not significantly different from the young subjects at baseline. They also responded as well as the young subjects… CONTINUE READING