The effect of ethinylestradiol (EE)/cyproterone acetate (CA) and EE/CA plus metformin treatment on adhesion molecules in cases with polycystic ovary syndrome (PCOS).

@article{Bilgir2009TheEO,
  title={The effect of ethinylestradiol (EE)/cyproterone acetate (CA) and EE/CA plus metformin treatment on adhesion molecules in cases with polycystic ovary syndrome (PCOS).},
  author={Oktay Bilgir and Levent Kebapcilar and Cuneyt Eftal Taner and Ferda Bilgir and Ayse Gul Kebapcilar and Giray Bozkaya and Yaşar Yildiz and Arif Yuksel and Ismail Sari},
  journal={Internal medicine},
  year={2009},
  volume={48 14},
  pages={1193-9}
}
OBJECTIVE To determine if EE/CA and EE/CA plus metformin treatment have any effect on adhesion molecules in cases with PCOS. METHODS Among 40 patients diagnosed with PCOS, one study arm was administered EE/CA (n=20, cyproterone acetate 2 mg, ethinylestradiol 35 microg) and the other was administered metformin (1,700 mg) combined with EE/CA (n=20, cyproterone acetate 2 mg, ethinylestradiol 35 microg). Soluble intercellular adhesion molecule-1 (sICAM-1), soluble endothelial leukocyte adhesion… CONTINUE READING