The effect of erythropoietin on normal and neoplastic cells

@inproceedings{Elliott2012TheEO,
  title={The effect of erythropoietin on normal and neoplastic cells},
  author={Steve Elliott and A. Macgregor Sinclair},
  booktitle={Biologics : targets & therapy},
  year={2012}
}
Erythropoietin (Epo) is an essential hormone that binds and activates the Epo receptor (EpoR) resident on the surface of erythroid progenitor cells, thereby promoting erythropoiesis. Recombinant human erythropoietin has been used successfully for over 20 years to treat anemia in millions of patients. In addition to erythropoiesis, Epo has also been reported to have other effects, such as tissue protection and promotion of tumor cell growth or survival. This became of significant concern in 2003… CONTINUE READING
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