The effect of environmental hypercapnia and salinity on the expression of NHE-like isoforms in the gills of a euryhaline fish (Fundulus heteroclitus).

@article{Edwards2005TheEO,
  title={The effect of environmental hypercapnia and salinity on the expression of NHE-like isoforms in the gills of a euryhaline fish (Fundulus heteroclitus).},
  author={Susan L. Edwards and Brian P Wall and Alison I Morrison-Shetlar and Samuel Sligh and Jill C Weakley and James B. Claiborne},
  journal={Journal of experimental zoology. Part A, Comparative experimental biology},
  year={2005},
  volume={303 6},
  pages={464-75}
}
The current models for branchial acid excretion in fishes include Na(+)/H(+) exchange and the electrogenic excretion of H+ via H+-ATPase. The predominant route of acid excretion in some freshwater fishes is thought to be via the H+-ATPase/Na+ channel system. The euryhaline Fundulus heteroclitus may not fit this profile even when adapted to freshwater (FW). We hypothesize that the Na+/H+ exchanger (NHE) in this species may play a predominant role in acid-base regulation for both marine and FW… CONTINUE READING

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