The effect of environmental humidity and temperature on skin barrier function and dermatitis

  title={The effect of environmental humidity and temperature on skin barrier function and dermatitis},
  author={Kristiane A. Engebretsen and Jeanne Duus Johansen and Sanja Ke{\vz}i{\'c} and Allan Linneberg and J.P. Thyssen},
  journal={Journal of the European Academy of Dermatology and Venereology},
Physicians are aware that climatic conditions negatively affect the skin. In particular, people living in equator far countries such as the Northern parts of Europe and North America are exposed to harsh weather during the winter and may experience dry and itchy skin, or deterioration of already existing dermatoses. We searched the literature for studies that evaluated the mechanisms behind this phenomenon. Commonly used meteorological terms such as absolute humidity, relative humidity and dew… 

Has dry/cold weather an impact on the skin condition of cleanroom workers?

Assessing whether a similar effect might be observed in cleanroom workers, occupationally exposed to strictly controlled ambient conditions, found work in a strictly controlled environment with prolonged wearing of occlusive gloves, with clean hands and without exposure to additional hazardous substances did not seem to negatively affect the skin.

Exposure to cold airflow alters skin pH and epidermal filaggrin degradation products in children with atopic dermatitis.

  • M. JungInsung Kim Jihyun Kim
  • Medicine
    Allergology international : official journal of the Japanese Society of Allergology
  • 2019

Climatic Effect on Atopic Dermatitis Course and Therapeutic Capabilities

This review shows how climate and environmental changes can affect the course of AD and the data on utilization efficiency of emollient plus for moderating of climatic conditions adverse effects on epidermal structures at patients with AD is presented.

The Effects of Regional Climate and Aging on Seasonal Variations in Chinese Women’s Skin Characteristics

Skin hydration and barrier function decreased more during a cold, dry winter than summer, and the barrier dysfunctions such as an increase in TEWL and pH occurred more commonly in old age groups.

The Role of the Environment and Exposome in Atopic Dermatitis

This review examines the biological effects of key environmental exposures at the population, community and individual levels in order to describe their effect on AD pathogenesis and specifically emphasises the timing and dosage of exposures and its effect on the cellular and molecular pathways implicated in AD.

Unravelling effects of relative humidity on lipid barrier formation in human skin equivalents

It is demonstrated that RH directly influences epidermal morphogenesis, albeit the in vitro lipid barrier formation is comparable at 90% and 60% RH.

Clinical Aspects of Irritant Contact Dermatitis

Therapy and prevention require identification of irritants and reduction of skin contact by gloves or technical measures, and sensitization to environmental allergens does exist and is frequently associated with previous atopic dermatitis.



Regulation of the cutaneous allergic reaction by humidity

This study demonstrated that the cutaneous immune reaction is regulated by environmental humidity and suggested 2 possible mechanisms, i.e., increase in Langerhans cells and increased penetration of allergen with low humidity.

Significance of humidity and temperature on skin and upper airway symptoms.

Assessment of the effect of absolute and relative humidity, temperature and humidification on workers' skin and upper airway symptoms, and perceptions in the office environment found that skin dryness and rash, pharyngeal dryness, and nasal drys and congestion are alleviated in higher humidity.

Influence of climatic conditions on the irritant patch test with sodium lauryl sulphate.

A strong correlation was observed between temperature, steam pressure, absolute and relative humidity and the increase in TEWL, and most pronounced during winter and spring, and provide experimental confirmation of epidemiological studies in which the incidence of irritant skin changes was found to be increased during the winter season with cold and dry air.

The Winter Season Affects More Severely the Facial Skin than the Forearm Skin: Comparative Biophysical Studies Conducted in the Same Japanese Females in Later Summer and Winter

The obtained data suggest that the exposed facial skin becomes more irritable under the influence of the dry and cold environment of winter even in healthy individuals where the barrier function of the SC is relatively poor as compared to the skin of other areas.

Skin barrier integrity and natural moisturising factor levels after cumulative dermal exposure to alkaline agents in atopic dermatitis.

The pronounced decrease of NMF after repeated single and sequential irritant exposure may be a pathogenetically relevant factor for development of chronic irritant contact dermatitis in both healthy and atopic individuals.

Influence of weather and climate on subjective symptom intensity in atopic eczema

The results show that itching in atopic eczema is significantly dependent on meteorological conditions, and suggest that a certain range of thermo-hygric atmospheric conditions with a balance of heat and water loss on the skin surface is essential for the skin to feel comfortable.

Meteorological influence on NaOH irritation varies with body site

Unlike skin challenge with sodium lauryl sulphate, challenge with NaOH on a body area not directly exposed to environmental factors (FA) seems robust against seasonal influences and may provide supporting evidence to help identify individuals with atopic skin.

Physiological and subjective responses to low relative humidity.

It was obvious that low RH affects SCT, the dryness of the ocular mucosa and the stratum corneum of the skin and causes a decrease in mean skin temperature.

Methods to Assess the Protective Efficacy of Emollients against Climatic and Chemical Aggressors

The two presented test methods can be used for evaluation of protective effect of emollient, by reinforcing the barrier function against experimentally induced skin dehydration, with a significant difference in variation between both areas.