The effect of enalapril on glomerular growth and glomerular lesions after subtotal nephrectomy in the rat: a stereological analysis.

@article{Amann1993TheEO,
  title={The effect of enalapril on glomerular growth and glomerular lesions after subtotal nephrectomy in the rat: a stereological analysis.},
  author={Kerstin Amann and T Irzyniec and Gerhard Mall and Eberhard Ritz},
  journal={Journal of hypertension},
  year={1993},
  volume={11 9},
  pages={969-75}
}
INTRODUCTION Angiotensin converting enzyme (ACE) inhibitors have a beneficial effect on glomerular injury in different models of renal damage. Their presumed nephroprotective action has been related partly to actions on glomerular growth. We examined the effect of prophylactic administration of a moderate dose of enalapril (50 mg/l in drinking water) in male Sprague-Dawley rats on a diet containing 40% protein and moderate NaCl. METHODS The rats were followed for 8 weeks after subtotal… CONTINUE READING