The effect of emetine on the immune response of mice.

Abstract

Emetine (33 mg/kg body weight) administered intraperitoneally blocked the immune response of mice to 10(9) sheep red blood cells (SRBC). The inhibition was almost complete when the drug was administered simultaneously or 24 hr after immunization, while partial inhibition was caused by treatment at 48 and 72 hr. Incorporation of 14C-leucine and 3H-thymidine… (More)

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