The effect of elastase-specific monoclonal and polyclonal antibodies on the virulence ofAspergillus fumigatus in immunocompromised mice

Abstract

Elastase has been implicated as a potential virulence factor involved in the invasion process of the opportunistic pathogen,Aspergillus fumigatus. Monoclonal and polyclonal antibodies, known to inhibit elastase in vitro, were employed in an immunocompromised mouse model of invasive aspergillosis to determine if the antibodies could protect mice from fatal… (More)
DOI: 10.1007/BF01371095

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@article{Frosco1994TheEO, title={The effect of elastase-specific monoclonal and polyclonal antibodies on the virulence ofAspergillus fumigatus in immunocompromised mice}, author={M Frosco and Theodore Chase and James D. Macmillan}, journal={Mycopathologia}, year={1994}, volume={125}, pages={65-76} }