The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand binding.

@article{Murrough2011TheEO,
  title={The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand binding.},
  author={James W. Murrough and Christoph Czermak and Shannan Henry and Nabeel Nabulsi and Jean-Dominique Gallezot and Ralitza Gueorguieva and Beata Planeta-Wilson and John H. Krystal and John F. Neumaier and Yiyun Huang and Yu-Shin Ding and Richard E. Carson and Alexander Neumeister},
  journal={Archives of general psychiatry},
  year={2011},
  volume={68 9},
  pages={892-900}
}
CONTEXT Serotonergic dysfunction is implicated in the pathogenesis of posttraumatic stress disorder (PTSD), and recent animal models suggest that disturbances in serotonin type 1B receptor function, in particular, may contribute to chronic anxiety. However, the specific role of the serotonin type 1B receptor has not been studied in patients with PTSD. OBJECTIVE To investigate in vivo serotonin type 1B receptor expression in individuals with PTSD, trauma-exposed control participants without… CONTINUE READING
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Arch Gen Psychiatry/ Vol 68 (no

  • ES Kubany, SN Haynes, +4 authors K. Burns
  • SEP 2011 WWW.ARCHGENPSYCHIATRY.COM
  • 2011
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