The effect of early goal-directed therapy for treatment of severe sepsis or septic shock: A systemic review and meta-analysis.

Abstract

PURPOSE To assess the effects of early goal-directed therapy (EGDT) on reducing mortality compared with conventional management of severe sepsis or septic shock. MATERIALS AND METHODS We included a systemic review, using the Medline and EMBASE. Seventeen randomized trials with 5765 patients comparing EGDT with usual care were included. RESULTS There… (More)
DOI: 10.1016/j.jcrc.2016.10.019

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