The effect of dobutamine infusion on fractional diaphragm thickening and diaphragm blood flow during fatigue.

@article{SmithBlair2003TheEO,
  title={The effect of dobutamine infusion on fractional diaphragm thickening and diaphragm blood flow during fatigue.},
  author={N. Smith-Blair and J. Pierce and R. Clancy},
  journal={Heart \& lung : the journal of critical care},
  year={2003},
  volume={32 2},
  pages={
          111-20
        }
}
BACKGROUND Diaphragm fatigue (DF) has been implicated in respiratory failure in diseases that increase inspiratory resistance loading (IRL) and may complicate weaning of patients from mechanical ventilation. OBJECTIVE The purpose of this study was to examine the effects of dobutamine administration (10 micro g/kg/min) on DF and to identify the mechanisms by which dobutamine augments diaphragm shortening and diaphragm blood flow (DBF) during fatigue with a rat model. METHODS The study had an… Expand
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