The effect of dimethylbenz(a)anthracene on murine hematopoiesis

  title={The effect of dimethylbenz(a)anthracene on murine hematopoiesis},
  author={Hans Joachim Seidel},
  journal={Zeitschrift f{\"u}r Krebsforschung und Klinische Onkologie},
DMBA was given p.o. to young adult female CBA/J mice in two regimens, a single dose of 1 mg and 4 doses of 1 mg in weekly intervals. In the peripheral blood only a transient reticulocytopenia and thrombocytopenia was observed in both groups. After 4 doses the thymus and spleen weights were reduced up to 4 weeks after the last dose. In the bone marrow the… CONTINUE READING