The effect of different digoxin concentrations on heart tissue and antioxidant status in iron-overloaded rats

@article{Shahouzehi2018TheEO,
  title={The effect of different digoxin concentrations on heart tissue and antioxidant status in iron-overloaded rats},
  author={B. Shahouzehi and H. R. Nasri and Y. masoumi-ardakani},
  journal={ARYA Atherosclerosis},
  year={2018},
  volume={14},
  pages={46 - 52}
}
  • B. Shahouzehi, H. R. Nasri, Y. masoumi-ardakani
  • Published 2018
  • Medicine
  • ARYA Atherosclerosis
  • BACKGROUND Thalassaemia is a hereditary disorder and has an economic burden on patients and the government. The most prevalent complication in these patients is iron overload which is followed by cardiomyopathy. Digoxin is considered as a treatment against heart failure in thalassaemia. The present study evaluated the effect of two digoxin concentrations on iron content and antioxidative defense in cardiac tissue of iron-overloaded rats. METHODS The study was conducted on 48 rats which were… CONTINUE READING

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