Corpus ID: 12546575

The effect of different antioxidants on nitric oxide production in hypertensive rats.

@article{Kojov2006TheEO,
  title={The effect of different antioxidants on nitric oxide production in hypertensive rats.},
  author={Stanislava Koj{\vs}ov{\'a} and L{\'y}dia Jendekov{\'a} and Josef Zicha and Jaroslav Kune{\vs} and Ramaroson Andriantsitohaina and Olga Pechanova},
  journal={Physiological research},
  year={2006},
  volume={55 Suppl 1},
  pages={
          S3-16
        }
}
The imbalance between nitric oxide (NO) and reactive oxygen species (ROS) production appears to be a common feature of experimental and human hypertension. Previously, different antioxidants and/or scavengers of oxygen free radicals were shown to activate nitric oxide synthase (NO synthase, NOS) and to increase the expression of both endothelial and neuronal NO synthase isoforms leading to blood pressure reduction. On the other hand, various antihypertensive drugs have been documented to… Expand
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