The effect of dietary nitrate on salivary, plasma, and urinary nitrate metabolism in humans.

@article{Pannala2003TheEO,
  title={The effect of dietary nitrate on salivary, plasma, and urinary nitrate metabolism in humans.},
  author={Ananth Sekher Pannala and Ali R Mani and Jeremy P. E. Spencer and Vernon O Skinner and Karl Richard Bruckdorfer and Kevin P. Moore and Catherine A. Rice-Evans},
  journal={Free radical biology & medicine},
  year={2003},
  volume={34 5},
  pages={576-84}
}
Dietary nitrate is metabolized to nitrite by bacterial flora on the posterior surface of the tongue leading to increased salivary nitrite concentrations. In the acidic environment of the stomach, nitrite forms nitrous acid, a potent nitrating/nitrosating agent. The aim of this study was to examine the pharmacokinetics of dietary nitrate in relation to the formation of salivary, plasma, and urinary nitrite and nitrate in healthy subjects. A secondary aim was to determine whether dietary nitrate… CONTINUE READING
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