The effect of dietary fat content on phospholipid fatty acid profile is muscle fiber type dependent.

  title={The effect of dietary fat content on phospholipid fatty acid profile is muscle fiber type dependent.},
  author={Alena Janovsk{\'a} and George Hatzinikolas and Mark Mano and Gary A. Wittert},
  journal={American journal of physiology. Endocrinology and metabolism},
  volume={298 4},
A high-saturated-fat diet (HFD) induces obesity and insulin resistance (IR). IR has been linked to alterations and increased saturation in the phospholipid composition of skeletal muscles. We aimed to determine whether HFD feeding affects fatty acid (FA) membrane profile in a muscle fiber type-specific manner. We measured phospholipid FAs and expression of FA synthesis genes in oxidative soleus (SOL) and glycolytic extensor digitorum longus (EDL) muscles from rats fed either standard chow… 

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