The effect of dietary curcumin and capsaicin on hepatic fetuin-A expression and fat accumulation in rats fed on a high-fat diet

  title={The effect of dietary curcumin and capsaicin on hepatic fetuin-A expression and fat accumulation in rats fed on a high-fat diet},
  author={Muhammed Seyithanoğlu and Yıldız {\"O}ner-İyidoğan and Semra Doǧru-Abbasoǧlu and Sevda Tanrıkulu-K{\"u}ç{\"u}k and Hikmet Koçak and Şule Beyhan-{\"O}zdaş and Necla Koçak-Toker},
  journal={Archives of Physiology and Biochemistry},
  pages={102 - 94}
Abstract Effects of curcumin (turmeric) and capsaicin (red pepper) on hepatic fat accumulation and fetuin-A expression in rats fed high-fat diet (HFD) is aimed to be investigated. Male Sprague–Dawley rats received HFD (60% of total calories from fat) and 0.15 g capsaicin/kg HFD and/or 1.5 g curcumin/kg HFD for 16 weeks. Hepatic AMPK, p-AMPK and fetuin-A expressions were determined by western blotting, liver lipid levels were measured with colorimetric methods and serum fetuin-A, insulin, leptin… 

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