The effect of dibutyryl cyclic AMP on cultivated glial cells from corpus callosum of 30-day-old rats.

@article{Lodin1979TheEO,
  title={The effect of dibutyryl cyclic AMP on cultivated glial cells from corpus callosum of 30-day-old rats.},
  author={Zdeněk Lodin and J. Faltin and P. Koř{\'i}nkov{\'a}},
  journal={Physiologia Bohemoslovaca},
  year={1979},
  volume={28 2},
  pages={105-11}
}
1) Fragments of corpus callosum of 30-day-old rats were cultivated in Rose chambers. Mature astrocytes and predominantly differentiated oligodendroglial cells are present in the corpus callosum of rats at this age. 2) In vitro, astrocytes dedifferentiated into epithelial--like flattened cells, which highly adhered to the surface. Cells exhibited signs of phagocytosis, and their ultrastructure differed from differentiated cells, especially by the absence of microtubules and microfilaments. 3… CONTINUE READING