The effect of cyclosporine on canine lymphocyte activity.

Cyclosporine is a potent new immunosuppressive agent that has an important role in organ transplantation. The exact mechanism of action of this agent is unclear. The present study was designed to demonstrate the effects of a single dose infusion of cyclosporine on canine leukocyte subsets and on the functional capabilities of T cells from these animals. The… CONTINUE READING