The effect of cycloheximide on natural and X-ray-induced cell death in the developing cerebral cortex.


Naturally occurring cell death in the cerebral cortex and subcortical white matter is increased after X-irradiation, and this process is curbed with cycloheximide, an inhibitor of protein synthesis. However, cycloheximide alone increases cell death during development, and this effect is dose-dependent. This suggests that, in both normal and experimentally… (More)


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