The effect of curcumin and its nanoformulation on adjuvant-induced arthritis in rats

@inproceedings{Zheng2015TheEO,
  title={The effect of curcumin and its nanoformulation on adjuvant-induced arthritis in rats},
  author={Zhaoling Zheng and Yanhua Sun and Ziliang Liu and Mingqin Zhang and Chunqing Li and Hui Cai},
  booktitle={Drug design, development and therapy},
  year={2015}
}
BACKGROUND Rheumatoid arthritis (RA), induced by the prolonged inappropriate inflammatory responses, is one of the most prevalent of all chronic inflammatory joint diseases. Curcumin (CM), a yellow hydrophobic polyphenol derived from the herb turmeric, has various pharmacological activities against many chronic diseases and acts by inhibiting cell proliferation and metastasis and downregulating various factors, including nuclear factor kappa B, interleukin-1β and TNF-α. Given the pathogenesis… CONTINUE READING
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