The effect of cryosurgery and polymethylmethacrylate in dogs with experimental bone defects comparable to tumor defects.

@article{Malawer1988TheEO,
  title={The effect of cryosurgery and polymethylmethacrylate in dogs with experimental bone defects comparable to tumor defects.},
  author={Martin M. Malawer and Mary Marks and Dan McChesney and M Piasio and Scott Gunther and B M Schmookler},
  journal={Clinical orthopaedics and related research},
  year={1988},
  volume={226},
  pages={299-310}
}
The effects of liquid nitrogen (LN) and polymethylmethacrylate (PMMA) on normal bone, bone graft incorporation, and reossification were evaluated by simulating a tumor in dogs with experimental bone cavity. Ten skeletally mature mongrel dogs (20 femora) were divided into three groups: Group I, controls; Group II, LN (with and without bone graft); and Group III, PMMA (with and without LN). Roentgenograms, whole-mount histology, and tetracycline fluorescence studies were performed on the distal… CONTINUE READING

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